Fogarty HIV Research Training Program for Low-and Middle-Income Country Institutions (D43 Clinical Trial Optional) | PAR 22 151

Opportunity Information: Apply for PAR 22 151

The Fogarty HIV Research Training Program for Low-and Middle-Income Country Institutions (D43 Clinical Trial Optional) is a National Institutes of Health (NIH) grant opportunity designed to build and strengthen HIV research capacity in low- and middle-income countries (LMICs). The core aim is to support structured research training programs that help LMIC institutions develop the people, skills, and research environment needed to carry out high-quality HIV research that directly matches the realities of the HIV epidemic in their own countries. In practical terms, this program is about developing sustainable scientific capacity locally, not just supporting one-off trainings or short-term research activities.

This funding opportunity supports training across the full HIV prevention-to-care continuum, meaning proposed programs can focus on topics ranging from preventing new infections to improving treatment outcomes, long-term care, and quality of life for people living with HIV. The scope is intentionally broad and can include basic science, epidemiology, clinical research, behavioral and social science research, and community-based approaches. It also explicitly includes implementation science and the kinds of applied research that health systems often need most, such as operations research, health services research, and health systems research. Another emphasized theme is cross-disciplinary work, encouraging programs that integrate multiple fields to address complex real-world HIV challenges. The FOA also recognizes that HIV rarely exists in isolation, so training that addresses HIV-associated comorbidities and coinfections that shape the epidemic in a given setting is within scope.

A key expectation is that an application will not try to cover everything at once. Instead, it should concentrate the training plan around a clearly defined, high-priority HIV scientific area. That priority area should align with NIH HIV/AIDS research priorities referenced in NOT-OD-20-018. The training program should be anchored at a specific LMIC institution and may also include collaborating LMIC partner institutions, reflecting the goal of building institutional and regional research ecosystems rather than relying primarily on external capacity.

Administratively, this is a discretionary NIH grant in the education and health activity areas, offered under Funding Opportunity Number PAR-22-151. It uses the D43 mechanism, which is commonly used by NIH to support international research training programs and institutional capacity building. The listing includes multiple CFDA numbers (93.121, 93.242, 93.279, 93.313, 93.398, 93.989), reflecting that multiple NIH Institutes and Centers may participate or that the program aligns with several NIH funding lines. The announcement was created on 2022-04-21, and the original closing date shown is 2024-08-22. The notice indicates that clinical trials are optional, meaning applicants may propose training that involves clinical trial-related research skills and experiences, but they are not required to include a clinical trial component.

Eligibility is broad enough to accommodate a range of institutional applicants while still centering LMIC capacity building. Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, and nonprofit organizations (both those with and without 501(c)(3) status, as specified). The FOA also calls out additional eligible applicant types, including non-U.S. entities (foreign organizations) and several categories of U.S.-based institutions that serve historically underrepresented populations, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Alaska Native and Native Hawaiian Serving Institutions, and Tribally Controlled Colleges and Universities (TCCUs). Overall, the eligibility framing supports partnerships and applications that can credibly deliver high-quality research training while keeping the long-term benefits focused on strengthening LMIC institutions and their ability to conduct HIV research that is locally relevant, scientifically rigorous, and responsive to evolving epidemic needs.

• The National Institutes of Health in the education, health sector is offering a public funding opportunity titled "Fogarty HIV Research Training Program for Low-and Middle-Income Country Institutions (D43 Clinical Trial Optional)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.121, 93.242, 93.279, 93.313, 93.398, 93.989.
• This funding opportunity was created on 2022-04-21.
• Applicants must submit their applications by 2024-08-22. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Eligible applicants include: Public and State controlled institutions of higher education, Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, Others.

Apply for PAR 22 151

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