Opportunity Information: Apply for PAR 17 004

Secondary Analyses of Existing Datasets in Heart, Lung, and Blood Diseases and Sleep Disorders (R21) is a National Institutes of Health funding opportunity (PAR 17-004) designed to spark new discoveries by encouraging researchers to re-use existing human datasets rather than collecting new data. The program sits within the NHLBI mission space, meaning it is aimed at questions that can advance knowledge in heart, lung, and blood diseases as well as sleep disorders. The central idea is to make strong, focused use of already-collected data to test novel hypotheses, explore new analytic angles, or develop and apply new tools, methods, models, or technologies that could meaningfully move biomedical or biobehavioral research forward.

The emphasis is explicitly on secondary analysis, meaning applicants are expected to work with datasets that already exist and were originally collected for a different primary purpose. Projects can be related to the original study goals, but they must be clearly distinct from the original specific aims. In other words, the application needs to show that it is not simply continuing the original project or repeating its planned analyses, but instead is taking the existing data in a new direction, such as asking a different scientific question, applying a new conceptual framework, using a different methodological approach, or examining outcomes, subgroups, exposures, or mechanisms that were not central to the original design. The opportunity does not support the collection of new data, so the proposed work should be feasible using available data resources (including appropriate permissions and access) and should be scoped to what can be accomplished through secondary analyses.

The award mechanism is an R21, which is typically used for exploratory or developmental research that can generate high-impact insights or set the stage for larger studies. The listing includes an award ceiling of $75,000, indicating the maximum amount available under this opportunity as presented in the source information. The funding instrument type is a grant, and the activity category is health, with CFDA numbers 93.233, 93.837, 93.838, 93.839, and 93.840 associated with NIH/NHLBI program areas.

Eligibility is broad and includes many types of organizations that might be positioned to conduct secondary analyses. Eligible applicants include state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; tribal organizations other than federally recognized governments; public housing authorities and Indian housing authorities; nonprofits with and without 501(c)(3) status (other than institutions of higher education); for-profit organizations other than small businesses; small businesses; and other entities. The announcement also highlights additional eligible applicants such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal agencies, regional organizations, non-domestic (non-U.S.) entities (foreign organizations), Indian/Native American tribal governments other than federally recognized, and U.S. territories or possessions. This wide eligibility reflects an intent to draw ideas from many sectors and communities, including institutions that serve historically underrepresented populations and organizations outside the United States when appropriate.

Administratively, the sponsoring agency is the National Institutes of Health. The source record shows a creation date of 2016-10-06 and an original closing date of 2019-10-30. As described, the purpose is not simply to encourage re-analysis for efficiency, but to motivate creative, high-yield use of existing data resources so that valuable datasets can produce additional knowledge beyond what was originally planned, especially when that new knowledge could have significant impact on NHLBI-relevant conditions and sleep health.

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "Secondary Analyses of Existing Datasets in Heart, Lung, and Blood Diseases and Sleep Disorders (R21)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.233, 93.837, 93.838, 93.839, 93.840.
  • This funding opportunity was created on 2016-10-06.
  • Applicants must submit their applications by 2019-10-30. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $75,000.00 in funding.
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
Apply for PAR 17 004

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Frequently Asked Questions (FAQs)

What is the name of this funding opportunity?

The opportunity is titled Secondary Analyses of Existing Datasets in Heart, Lung, and Blood Diseases and Sleep Disorders (R21).

What is the opportunity number or identifier?

The funding opportunity is identified as PAR 17-004.

Which agency is sponsoring this opportunity?

The sponsoring agency is the National Institutes of Health (NIH).

Which mission area does it fall under?

It sits within the National Heart, Lung, and Blood Institute (NHLBI) mission space, focusing on heart, lung, and blood diseases as well as sleep disorders.

What is the main purpose of this program?

The program is designed to spark new discoveries by encouraging researchers to re-use existing human datasets rather than collecting new data, with an emphasis on generating meaningful advances in biomedical or biobehavioral research relevant to NHLBI and sleep health.

What does "secondary analysis" mean in this announcement?

Secondary analysis means working with datasets that already exist and that were originally collected for a different primary purpose, and using them to pursue new questions or approaches.

Does this opportunity support collecting new data?

No. The opportunity explicitly emphasizes secondary analysis and states that it does not support the collection of new data. Proposed work should be feasible using available data resources (including having appropriate permissions and access).

Do projects have to be unrelated to the original study goals?

Not necessarily. Projects can be related to the original study goals, but they must be clearly distinct from the original specific aims.

How do applicants show their proposal is distinct from the original project?

Based on the announcement description, applications should demonstrate they are not continuing the original project or repeating planned analyses. Instead, they should take the existing data in a new direction, such as:

  • Asking a different scientific question
  • Applying a new conceptual framework
  • Using a different methodological approach
  • Examining outcomes, subgroups, exposures, or mechanisms not central to the original design

What types of research activities are encouraged?

The opportunity encourages strong, focused use of existing datasets to:

  • Test novel hypotheses
  • Explore new analytic angles
  • Develop and apply new tools, methods, models, or technologies

The overall intent is to move biomedical or biobehavioral research forward in NHLBI-relevant areas and sleep disorders.

What is the award mechanism?

The mechanism is an R21, which is typically used for exploratory or developmental research intended to generate high-impact insights or help set the stage for larger studies.

What is the maximum award amount mentioned?

The listing includes an award ceiling of $75,000, indicating the maximum amount available under this opportunity as presented in the source information.

What is the funding instrument type?

The funding instrument type is a grant.

What is the activity category?

The activity category is listed as health.

Which CFDA numbers are associated with this opportunity?

The opportunity lists the following CFDA numbers: 93.233, 93.837, 93.838, 93.839, and 93.840.

Who is eligible to apply?

Eligibility is broad and includes many organization types, including:

  • State, county, and city or township governments
  • Special district governments
  • Independent school districts
  • Public and state-controlled institutions of higher education
  • Private institutions of higher education
  • Federally recognized Native American tribal governments
  • Tribal organizations other than federally recognized governments
  • Public housing authorities and Indian housing authorities
  • Nonprofits with and without 501(c)(3) status (other than institutions of higher education)
  • For-profit organizations other than small businesses
  • Small businesses
  • Other entities

Are minority-serving institutions and community-based organizations eligible?

Yes. The announcement highlights additional eligible applicants such as:

  • Alaska Native and Native Hawaiian Serving Institutions
  • Asian American Native American Pacific Islander Serving Institutions (AANAPISIs)
  • Hispanic-serving Institutions
  • Historically Black Colleges and Universities (HBCUs)
  • Tribally Controlled Colleges and Universities (TCCUs)
  • Faith-based or community-based organizations

Are federal agencies eligible to apply?

Yes. The announcement lists eligible federal agencies among additional eligible applicants.

Are non-U.S. entities eligible to apply?

Yes. The announcement includes non-domestic (non-U.S.) entities (foreign organizations) as eligible applicants.

Are U.S. territories or possessions eligible to apply?

Yes. The announcement includes U.S. territories or possessions among eligible applicants.

What does the program aim to achieve beyond efficiency?

Beyond efficiency, the stated goal is to motivate creative, high-yield use of existing data resources so that valuable datasets can produce knowledge beyond what was originally planned, especially when that knowledge could have significant impact on NHLBI-relevant conditions and sleep health.

What are the key feasibility expectations for applicants?

The proposed work should be feasible using available data resources, including having appropriate permissions and access, and should be scoped to what can be accomplished through secondary analyses.

What dates are shown for this opportunity in the source record?

The source record shows a creation date of 2016-10-06 and an original closing date of 2019-10-30.

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