Opportunity Information: Apply for CDC RFA OE20 20010101SUPP21

The grant opportunity titled "Enhancing Public Health Laboratory Capabilities and Increasing Capacity" is a CDC cooperative agreement designed to strengthen the ability of state, local, and territorial public health laboratories (PHLs) to carry out essential testing and other science-based services that support public health decision-making. The central idea is that public health laboratories sit at the core of the public health system: they generate the actionable laboratory data that epidemiologists, health officials, and policy makers rely on to detect threats, understand their scope, and decide which interventions are most effective. Because laboratory findings often drive real-time public health actions, the opportunity emphasizes improving both capability (what labs can do) and capacity (how much they can do, how quickly, and how reliably).

A key theme of the announcement is preparedness across a wide and growing set of health threats, with particular attention to infectious diseases and emergency response. The description explicitly references COVID-19 as an example of the kind of large-scale, fast-moving public health emergency that demands robust laboratory systems not only within the United States but also in coordination with global response needs. The intent is to ensure laboratories can detect and respond to new, emerging, and ongoing threats, which implies support for modernization, workforce and operational readiness, and systems that allow labs to scale up quickly during surges while maintaining quality and reliability.

Administratively, this is a discretionary funding opportunity from the U.S. Department of Health and Human Services, Centers for Disease Control and Prevention (CDC), specifically under CDC CSELS, using a cooperative agreement funding instrument. A cooperative agreement generally indicates that CDC expects to have substantial involvement during the period of performance, such as providing technical guidance, collaborating on implementation approaches, or shaping performance expectations, rather than simply issuing funds with minimal engagement. The funding activity category is Health, and the CFDA number listed is 93.322. The opportunity number is CDC RFA OE20 20010101SUPP21.

The opportunity was created on December 15, 2020, with an original application closing date of February 15, 2021. Applications were required to be submitted through Grants.gov by 11:59 pm Eastern Standard Time on the deadline date, underscoring the standard federal requirement that submissions be fully validated and successfully received by the system before the cutoff. The posted award ceiling is $3,000,000, and the announcement anticipates a single award (ExpectedAwards: 1), suggesting a targeted investment rather than a broad multi-recipient competition. Eligibility is indicated as "Others" with further clarification referenced in an additional eligibility section, meaning applicants would need to confirm they meet the specific eligibility terms described in the full notice rather than relying only on the short summary.

Overall, the grant is positioned as a capacity-building and readiness investment for public health laboratories, recognizing that laboratory data is tightly interwoven with epidemiology and broader public health operations. By enhancing laboratory capabilities and increasing capacity, the program aims to improve the speed, scale, and effectiveness of detecting health threats and informing interventions, especially during high-consequence events like the COVID-19 response.

  • The Department of Health and Human Services, Centers for Disease Control - CSELS in the health sector is offering a public funding opportunity titled "Enhancing Public Health Laboratory Capabilities and Increasing Capacity" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.322.
  • This funding opportunity was created on Dec 15, 2020.
  • Applicants must submit their applications by Feb 15, 2021 Explanation of Deadlines Application must be successfully submitted to Grants.gov by 1159 pm Eastern Standard Time on the deadline date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $3,000,000.00 in funding.
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
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